Junior Scientist Praha

Junior Scientist

Background

SOTIO is a mid-sized biotech company developing novel protein-based anti-cancer therapies. The main focus of the ADC Discovery team is on antibody-drug-conjugates (ADC), a rapidly emerging class of cancer therapeutics. This team is part of the very initial (discovery) and preclinical stage of drug development that enables you to have a direct impact on SOTIO’s development strategy, selection of a drug target and a clinical candidate molecule. The research and development are conducted in brand new laboratories with state-of-the-art equipment for drug testing.

Position Summary

We are looking for two proactive and curious early-career scientists to join our ADC Discovery team. As a successful candidate, you will become an integral member of a dynamic and highly collaborative environment, where you will get a unique opportunity to advance next-generation cancer therapeutics into the clinical phase. In this role, you will design and execute in vitro experiments to answer critical questions about molecules and targets under evaluation and present your findings in team meetings. You will study biology of the relevant proteins to support selection of the right target or adjustment of the structure of the candidate molecules to make them more efficient against tumor cells. You will closely collaborate with members of project teams to determine the right timing of activities, priorities and future plans.
 

Key Activities and Responsibilities:

• Design, execute and troubleshoot (mainly cell-based) in vitro assays

• Maintain accurate and detailed records of experiments

• Build protocols for the experiments

• Analyze and critically review data, prepare reports and presentations in English for internal meetings

• Proactively optimize processes around routine experiments to reduce workload and increase efficiency/speed

• Review relevant scientific literature and other available resources to increase team’s know-how, support the drug development and assay optimization

• Work both independently and as part of a collaborative team to achieve shared goals
   

Competence, Skills and Qualification:

• Master’s degree in cancer biology/cell biology/immunology/molecular biology or related fields

• Hands-on experience in cell culture, cell-based assays, flow cytometry and molecular biology techniques 

• Experience with proliferation, cytotoxicity, drug response assays and/or compound screening is an advantage

• Ability to conduct data analysis using Microsoft Excel, GraphPad PRISM, or equivalent software

• Experience in conducting literature reviews

• Oncology project background is an advantage

• Strong attention to detail in a rapidly changing environment and ability to work on multiple programs simultaneously

• Flexibility to acquire additional competencies and skillsets as needed

• A proactive, motivated, open-minded and self-organized person

• Knowledge of the English language on the advanced level (written and verbal communication skills) 

• Working with hazardous biological and chemical substances under the appropriate safety measures is part of the job description

• Hepatitis B vaccination will be required
   

Location:

• Českomoravská 2532/19b, 1900 00 Prague 9, Czech Republic

Join us and be part of a team committed to advancing science and improving the lives of oncology patients through innovative therapies. 
Apply by submitting your CV and a motivation letter.

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